anticholinergic

Blocks nervous transmission

Anticholinergic describes drugs or effects that block the neurotransmitter acetylcholine in the nervous system.

These medications treat conditions from motion sickness to overactive bladder, but cause side effects like dry mouth, blurred vision, and confusion—especially dangerous in elderly patients.

The anticholinergic effects of older antihistamines make them sedating.

peripheral

dry mouth

Insufficient saliva production

hyperthermia · flushing · photophobia · ileus · thirst

cognitive

delirium

Acute mental disorientation

disorientation · agitation · hallucination · sedation · drowsiness · brain fog · elderly · geriatric · polypharmacy · cognitive decline

toxicity

overdose

Harmful excess intake

coma · antidote · red · dry · blind · mad · hot · delirium

therapeutic

antispasmodic

Agent preventing muscle cramps

motion sickness · COPD · asthma · urinary incontinence · drooling · preoperative · anesthesia · dystonia · bradycardia · secretions

mechanism

receptor

Signal-receiving molecule

antagonist · binding · inhibition · synaptic · ganglionic · nicotinic · signal · nerve · pathway

medications

diphenhydramine

Sedating antihistamine compound

Opposites
cholinergic system effect

anticholinergiccholinergic

Acetylcholine-mediated neural signaling

parasympathomimetic

parasympathetic nervous system action

anticholinergicparasympathomimetic

Activates rest-digest pathways

physiological effect profile

anticholinergicbronchoconstrictor

Agent narrowing lung passages

stimulant

Family

anticholinergics

Familiarity
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Profile
Used worldwide · Timeless · Rated G