Diels-Alder
Diene plus dienophile
A Diels-Alder reaction is a chemical reaction in which a diene (a molecule with two double bonds) combines with a dienophile (a molecule with one double bond) to form a six-membered ring.
The reaction is fundamental to organic chemistry, used to build complex molecules efficiently: The Diels-Alder reaction created the ring structure needed for the synthesis.
Named after the German chemists who discovered it in 1928.
Highest academic honor
- 1950Mid-twentieth century year
- discoveryAct of finding something
- 1928A calendar year
- landmarkNotable point of reference
classic · textbook · Woodward · Hoffmann · organic chemistry · pioneering · milestone
Two C=C bonds present
- concertedJointly arranged or carried out
- endoPrefix meaning inside
- exoPrefix for outer
- synchronousOccurring at same moment
Conjugated four-carbon diene
- maleic anhydrideCyclic acid derivative
- furanAromatic oxygen-containing ring
- acrylateAcrylic acid derivative
- quinoneCyclic conjugated diketone
Compounds from organisms
- building blockBasic unit for construction
- convergentTending toward union
- complexityState of being complicated
- scaffoldTemporary elevated work structure
terpenes · alkaloids · steroids · pharmaceutical · drug discovery · methodology · strategy · disconnection
Right-angled prefix
- metaSelf-aware or transcendent
- paraMilitary skydiver, briefly
- asymmetricNot identical on both sides
- chiral auxiliaryDetachable asymmetric synthesis guide
Within a single molecule
- dominoRectangular game piece
- tandemSequential two-person arrangement
- carbonylC=O functional group
- photochemicalCaused by light radiation
Nobel Prize
Highest academic honor
landmark · classic · textbook · Woodward · Hoffmann · organic chemistry · pioneering · milestone
diene
Two C=C bonds present
synchronous · six-membered ring · electron flow · thermal · allowed
butadiene
Conjugated four-carbon diene
- maleic anhydrideCyclic acid derivative
- furanAromatic oxygen-containing ring
- acrylateAcrylic acid derivative
quinone · isoprene · conjugated · activated · substituted
natural products
Compounds from organisms
- building blockBasic unit for construction
- convergentTending toward union
- complexityState of being complicated
scaffold · terpenes · alkaloids · steroids · pharmaceutical · drug discovery · methodology · strategy · disconnection
ortho
Right-angled prefix
- metaSelf-aware or transcendent
- paraMilitary skydiver, briefly
- asymmetricNot identical on both sides
intramolecular
Within a single molecule
- chemical reactionscondensation, combustion, oxidation, hydrolysis, oxidation-reduction
- reaction mechanismsbond breaking, bond cleavage, SN1, SN2, elimination
- Alkene Reactionshydrogenation, bromination, chlorination, fluorination, metathesis
- Ring Reactionscyclization, ring closure
- rearrangementsrearrangement, reshuffle, reorder, permutation, transpose
- retrosynthesisdisconnection, transform, building block, fragmentation