tissue matching
Organ donor screening
Tissue matching is the process of determining how closely a donor's and recipient's tissues align immunologically before transplantation.
When tissues match well, the recipient's immune system is less likely to reject the transplanted organ or cells.
The process examines specific proteins on cell surfaces—particularly HLA (human leukocyte antigen) markers.
Close tissue matching is especially critical for bone marrow transplants: They found a tissue match through the donor registry.
- organ donorPerson who bequeaths body parts
- crossmatchBlood compatibility verification
- antigensImmunity-triggering foreign substances
- genetic markersIdentifiable DNA sequence locations
- allelesVariant forms of genes
antibodies · perfect match · PCR testing · kidney transplant · cytokines · polymorphism · leukocytes · donor · immune response · inheritance patterns · immune · recipient · blood · kidney · bone marrow transplant · cord blood · transplant team · biopsy
- HistocompatibilityMHC class II, HLA-B27, crossmatch, mismatch, match score
- transplant immunityallograft, graft rejection, transplant rejection, organ rejection, immunosuppression
- organ transplantsorgan donation, organ transplant, kidney transplant, heart transplant, liver transplant
- biological materialsblood, plasma, serum, bone marrow, stem cells
- transplantsorgan transplant, liver transplant, bone marrow transplant, kidney transplant, heart transplant
- immunologyimmune system, immune response, antibodies, antigens, immunity
tissue matchinggraft rejection
Immune destruction of transplant
transplant rejection · tissue rejection · incompatibility · organ rejection · mismatch