hydroxylated
Given oxygen-hydrogen groups
Hydroxylated describes a molecule that has had a hydroxyl group (an oxygen-hydrogen pair, -OH) added to it through chemical reaction.
The term appears in biochemistry and organic chemistry: hydroxylated vitamin D, hydroxylated fatty acids.
Many drugs and hormones must be hydroxylated in the liver before becoming active in the body.
Intoxicating hydroxyl compound
- phenolAromatic hydroxyl compound
- polyolMulti-hydroxyl alcohol compound
- glycolTwo-hydroxyl alcohol compound
- hydroquinoneAromatic compound, two OH groups
Metabolic chemical conversion
- detoxificationRemoving harmful substances internally
- hepaticRelating to liver
- sulfationLead sulfate crystal accumulation
- conjugationVerb form variation system
excretion · pharmacokinetics · drug metabolism · intermediates · bioactivation · CYP3A4 · CYP2D6 · polar
alcohol
Intoxicating hydroxyl compound
biotransformation
Metabolic chemical conversion
- detoxificationRemoving harmful substances internally
- hepaticRelating to liver
- sulfationLead sulfate crystal accumulation
conjugation · excretion · pharmacokinetics · drug metabolism · intermediates · bioactivation · CYP3A4 · CYP2D6 · polar · water-soluble
cofactor
Enzyme-activating compound
- active siteEnzyme region binding substrates
- substrateUnderlying supporting material
- catalysisAccelerating reactions without consumption
hydroxylatedunoxidized
Not combined with oxygen
unmodified · unconverted · reduced · native · pristine
oxygen, oxidation, oxidize, hydrogen, hydrolysis, hydroxyl, hydrolyze, hydroponic