dysphoric
Profoundly ill at ease
Dysphoric describes a state of unease, dissatisfaction, or emotional discomfort—the opposite of euphoric.
The term appears frequently in clinical contexts: gender dysphoria refers to distress from incongruence between one's gender identity and assigned sex.
More generally, someone dysphoric feels restless and unhappy without a clear external cause: The medication left her dysphoric and irritable.
Subdued, lasting sadness
- despondentDeeply discouraged, hopeless
- depressedPersistently sad, spiritless
- miserableWretchedly unhappy, dejected
- gloomyDark and dispiriting
downcast · hopeless · despair · dejected · disheartened · forlorn · crestfallen · desolate
Persistent apprehensive distress
- dreadIntense anticipatory fear
- uneaseMild persistent worry
- apprehensionNervous anticipation of trouble
- agitationDisturbed, restless state
panic · worry · nervousness · trepidation · angst · hypervigilance · overwhelm · distressed
Unhappiness with circumstances
- dissatisfactionState of being displeased
- disgruntledSullenly dissatisfied
- unfulfilledNot brought to completion
- disenchantedLost one's illusions
disillusioned · frustrated · unsatisfied · disaffected · resentful · alienated · disconnected · estranged
Emotionally disturbed, restless
- fidgetyNervously unable to settle
- antsyRestlessly eager or nervous
- jitteryAnxiously restless
- edgyTense and irritable
twitchy · uneasy · restive · tense · impatient · squirmy · fretful · jumpy
Absence of feeling
- emptinessAbsence of substance
- numbnessLoss of sensation
- flatnessAbsence of slope
- detachmentSeparation or emotional uninvolvement
hollowness · listlessness · indifference · lethargy · torpor · heaviness · sluggishness · fatigue
melancholy
Subdued, lasting sadness
- despondentDeeply discouraged, hopeless
- depressedPersistently sad, spiritless
- miserableWretchedly unhappy, dejected
gloomy · downcast · hopeless · despair · dejected · disheartened · forlorn · crestfallen · desolate · bleak
anxiety
Persistent apprehensive distress
- dreadIntense anticipatory fear
- uneaseMild persistent worry
- apprehensionNervous anticipation of trouble
agitation · panic · worry · nervousness · trepidation · angst · hypervigilance · overwhelm · distressed · troubled
discontent
Unhappiness with circumstances
- dissatisfactionState of being displeased
- disgruntledSullenly dissatisfied
- unfulfilledNot brought to completion
disenchanted · disillusioned · frustrated · unsatisfied · disaffected · resentful · alienated · disconnected · estranged · bitter
agitated
Emotionally disturbed, restless
edgy · twitchy · uneasy · restive · tense · impatient · squirmy · fretful · jumpy · skittish
apathy
Absence of feeling
detachment · hollowness · listlessness · indifference · lethargy · torpor · heaviness · sluggishness · fatigue · weariness
- gender dysphoriaDistress from body-identity mismatch