tetrahydrobiopterin
Tetrahydrobiopterin is a naturally occurring compound that serves as a cofactor for several enzymes in the body, particularly those involved in producing neurotransmitters like dopamine and serotonin.
Deficiencies can cause neurological problems and a form of phenylketonuria that doesn't respond to dietary treatment alone.
Often abbreviated BH4 in medical contexts.
cofactor
Protein that hastens reactions
- biosynthesisLiving production of molecules
- regenerationBiological self-repair process
- catalysisAccelerating reactions without consumption
- active siteEnzyme region binding substrates
clinical
Inherited amino acid disorder
- supplementationAdding to something insufficient
- newborn screeningMedical tests for infants
- genetic testingAnalysis for inherited disorders
- responsivenessReadiness to react
dietary management · dystonia · developmental delay · treatment · therapy · diagnosis
enzyme
Protein that hastens reactions
- biosynthesisLiving production of molecules
- regenerationBiological self-repair process
- catalysisAccelerating reactions without consumption
active site · binding · oxidation · reduction · folate · coenzyme
PKU
Inherited amino acid disorder
- supplementationAdding to something insufficient
- newborn screeningMedical tests for infants
- genetic testingAnalysis for inherited disorders
responsiveness · dietary management · dystonia · developmental delay · treatment · therapy · diagnosis
- Dopamine Precursorslevodopa, tyrosine, phenylalanine
- pteridines
- tyrosine biochemistrytyrosine, dopamine, norepinephrine, epinephrine, catecholamines
- Nitric Oxidenitric oxide, vasodilation, citrulline, blood pressure regulation, endothelium