reepithelialization
Wound surface restoration
Reepithelialization is the regrowth of epithelial tissue—the thin layer of cells covering body surfaces—over a wound or damaged area.
The process is central to wound healing, as epithelial cells migrate from the wound edges to restore the skin's protective barrier: Reepithelialization was complete within two weeks of the burn injury.
cellular
Undifferentiated cells with regenerative potential
- mitosisNuclear division producing identical cells
- differentiationRecognizing meaningful differences
- fibroblastsCollagen-producing connective tissue cells
- growth factorsProteins stimulating cell proliferation
healing
Outermost tissue layer
- wound closureSealing an open injury
- scar formationFibrous tissue replacing damaged skin
- tissue repairBiological wound healing process
- proliferationRapid increase in quantity
matrix
Structural body protein
- basement membraneExtracellular matrix beneath epithelia
- proteasesEnzymes cleaving peptide bonds
- scaffoldTemporary elevated work structure
- dermisLiving tissue under epidermis
clinical
Protective covering for injuries
- occlusionComplete closure or blockage
- debridementRemoving damaged tissue surgically
- skin graftTransplanted tissue covering wounds
- biomarkersMeasurable disease indicators
stem cells
Undifferentiated cells with regenerative potential
- mitosisNuclear division producing identical cells
- differentiationRecognizing meaningful differences
- fibroblastsCollagen-producing connective tissue cells
growth factors · basement membrane · cytokinesis · chemotaxis
epidermis
Outermost tissue layer
- wound closureSealing an open injury
- scar formationFibrous tissue replacing damaged skin
- tissue repairBiological wound healing process
collagen
Structural body protein
- basement membraneExtracellular matrix beneath epithelia
- proteasesEnzymes cleaving peptide bonds
- scaffoldTemporary elevated work structure
wound dressing
Protective covering for injuries
- occlusionComplete closure or blockage
- debridementRemoving damaged tissue surgically
- skin graftTransplanted tissue covering wounds