pharmacokinetic
Body processes medication
Pharmacokinetic describes how the body processes a drug—its absorption, distribution, metabolism, and elimination.
The term appears in medical and pharmaceutical contexts: pharmacokinetic studies, pharmacokinetic profile.
It answers what the body does to a drug, as opposed to pharmacodynamic, which concerns what the drug does to the body.
ADME
Process of taking in
- distributionAllocation across recipients
- metabolismCellular nutrient conversion
- excretionRemoval of metabolic waste
- bioavailabilityFraction reaching active circulation
half-life · clearance · first-pass effect · biotransformation · steady state
clinical
- loading doseLarge initial medication amount
- maintenance doseDrug amount preserving effect
- drug interactionSubstances altering each other's effects
- pharmacogenomicsGene-based drug response study
absorption
Process of taking in
- distributionAllocation across recipients
- metabolismCellular nutrient conversion
- excretionRemoval of metabolic waste
bioavailability · half-life · clearance · first-pass effect · biotransformation · steady state
drug monitoring
- loading doseLarge initial medication amount
- maintenance doseDrug amount preserving effect
- drug interactionSubstances altering each other's effects
creatinine clearance
Kidney waste-removal efficiency measure