incretins
Insulin-prompting gut hormones
Incretins are hormones released by the gut after eating that stimulate insulin secretion and help regulate blood sugar.
The two main incretins are GLP-1 and GIP.
Drugs that mimic or enhance incretin action—such as semaglutide (Ozempic, Wegovy)—have become widely used for treating diabetes and obesity.
State of being full
- fullnessState of being complete
- weight lossReduction in body mass
- hypothalamusSubthalamic regulatory brain region
- nauseaPre-vomiting stomach discomfort
Incretin mimetic medication
- antidiabeticMedication treating high blood sugar
- blood sugarCirculating glucose level
- hyperglycemiaAbnormally high blood glucose
- type 2 diabetesChronic insulin resistance condition
metformin · A1C · injectable
Receptor-binding trigger molecule
- analogueSomething functionally similar
- mimeticRelating to imitation
- receptorSignal-receiving molecule
- subcutaneousBelow the skin
injection · bioavailability · pharmacokinetics · dosing · titration · side effects · contraindications · clinical trials
Substance released by glands
- postprandialFollowing a meal
- endogenousOriginating from within
- circulatingMoving in a circuit
- half-lifePeriod for fifty-percent reduction
Maintenance of stable blood sugar
- postprandial glucoseBlood sugar after eating
- fasting glucoseBlood sugar measured unfed
satiety
State of being full
- fullnessState of being complete
- weight lossReduction in body mass
- hypothalamusSubthalamic regulatory brain region
semaglutide
Incretin mimetic medication
- antidiabeticMedication treating high blood sugar
- blood sugarCirculating glucose level
- hyperglycemiaAbnormally high blood glucose
agonist
Receptor-binding trigger molecule
subcutaneous · injection · bioavailability · pharmacokinetics · dosing · titration · side effects · contraindications · clinical trials · Ozempic
secretion
Substance released by glands
- postprandialFollowing a meal
- endogenousOriginating from within
- circulatingMoving in a circuit
glucose homeostasis
Maintenance of stable blood sugar
- postprandial glucoseBlood sugar after eating
- fasting glucoseBlood sugar measured unfed
incretinsglucagon
Pancreatic blood-sugar raiser
glucocorticoids · cortisol · epinephrine · insulin · growth hormone
increase, concrete, recruit, increased, increasing, crescent, accrue, increases, increment