coiled-coil

Intertwined alpha helices

A coiled-coil is a protein structural motif in which two or more alpha helices wind around each other like strands of rope.

This arrangement creates exceptional stability and appears throughout biology—in muscle fibers, hair keratin, and the stalks of molecular motors.

The term functions as both noun and adjective: coiled-coil domains, a coiled-coil structure.

proteins

keratin

Structural hair protein

muscle · hair · wool · silk · elasticity

research

crystallography

Study of atomic lattices

domain · motif · scaffold

structure

pitch

Frequency of sound

parallel · antiparallel · bundling · register · stability · periodicity

applications

biosensor

Biological chemical detection device

biomaterial · nanofiber · self-assembling · therapeutic · purification · nanotube

Categories
  • dimers
Opposites
structural complexity

coiled-coilsingle-stranded

Having one chain only

structural organization

coiled-coilunfolded

Opened from folds

denatured

secondary structure type

coiled-coilloop

Curve closing on itself

turn

Family

coil, coiled, coiling, coils, uncoiled, recoil, recoiled, recoiling, recoils

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