autophagic

Eating one's own

Autophagic describes the process by which cells break down and recycle their own components—damaged proteins, worn-out organelles, or other cellular debris.

The term comes from Greek roots meaning "self-eating." In biology and medicine, autophagic activity increases during starvation or stress: The researchers observed autophagic degradation of mitochondria.

Figuratively rare, but occasionally describes self-consuming processes.

cellular

lysosome

Digestive organelle in cells

LC3 · membrane · cytoplasm · organelle · vacuole

degradation

proteolysis

Enzymatic protein breakdown

digestion · recycling · clearance · acidification · hydrolase · self-digestion

pathology

neurodegeneration

Progressive loss of neurons

cardiomyopathy · cancer · infection · inflammation · aging · senescence · dysfunction · deficiency · impairment · disease

survival

stress response

Body's reaction to threat

quality control · damage control

metabolic

homeostasis

Biological internal stability maintenance

metabolites

Opposites
cellular degradation mechanism

autophagicaccumulative

Growing by addition

cellular building vs. breakdown

autophagicanabolic

Building complex molecules

biosynthetic · synthetic · proliferative · hypertrophic · accretive

Family

autophagy

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