twain
Literary word: two
Twain is an archaic or literary word meaning two, usually implying a pair that has been divided or separated: never the twain shall meet.
The phrase suggests two things so different they cannot be reconciled or brought together.
Outside this expression, twain survives mainly in nautical contexts and deliberate archaism. (Capitalized Twain is most often the pen name of American author Mark Twain.)