serosurvey

Population immunity snapshot

A serosurvey is a study that tests blood samples from a population to measure the presence of antibodies, typically to assess how widely an infection has spread.

Public health officials use serosurveys to estimate true infection rates, which often exceed confirmed case counts: The COVID serosurvey suggested a third of the city had already been exposed.

methodology

antibody testing

Detecting immune proteins in blood

study design · enrollment · consent · biobanking · laboratory analysis · quality control · data collection

epidemiology

herd immunity

Widespread resistance protecting all

susceptibility · attack rate · community spread · risk factors · vulnerable populations

immunology

antibodies

Proteins targeting pathogens

cross-reactivity · sensitivity · specificity · waning immunity · boosting · reinfection · epitope

Opposites
population vs. individual assessment

serosurveyclinical diagnosis

Identifying disease through examination

diagnostic testing · clinical evaluation

surveillance vs. intervention

serosurveyvaccination campaign

Organized mass immunization effort

mass vaccination · treatment program · outbreak response · disease eradication · prophylaxis

retrospective exposure vs. active infection detection

serosurveyPCR testing

Gene sequence amplification method

antigen testing

Family

survey, serum, sera, serous, serology, serological, serologist, seropositive, seronegative

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