cholestasis

Bile flow stoppage

Cholestasis is impaired or blocked flow of bile from the liver.

The condition causes bile to accumulate, leading to jaundice, itching, and dark urine.

Cholestasis can result from obstruction (gallstones, tumors) or from problems within liver cells themselves: The patient developed cholestasis after starting the new medication.

liver

cirrhosis

Irreversible hepatic scarring

  • hepatitisInflammatory liver condition
  • fibrosisPathological connective tissue buildup
  • ALTLiver function indicator

bilirubin · albumin · hepatomegaly · liver biopsy

symptoms

pruritus

Medical term for itching

yellowing · dark urine · fatigue · malabsorption · skin discoloration

bile

bilirubin

Hemoglobin degradation byproduct

secretion · excretion · conjugation · emulsification · micelles · bile salts · common bile duct · ursodeoxycholic acid

obstruction

blockage

Obstruction halting movement

compression · tumor · stenosis · atresia · impediment · narrowing · intrahepatic

causes

pregnancy

Carrying developing offspring

genetic · autoimmune · viral hepatitis · alcoholic

Family

cholesterol, stasis, hypercholesterolemia

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