drug-naïve
Never medicated before
Drug-naïve describes a patient who has never been treated with a particular medication or class of drugs: drug-naïve patients responded better to the initial therapy.
The term appears in clinical trials and medical literature to distinguish first-time users from those with prior exposure, since previous treatment may affect how someone responds to a drug.
research
Tested against inactive substance
- comparatorTwo-input magnitude decider
- preclinicalBefore human trials
- enrollmentAct of registering officially
- randomizationIntroducing chance systematically
stratification · cohort · efficacy · tolerability · pharmacokinetics · dose-response · titration · sensitivity
clinical
Not given care
- baselineStandard for comparison
- unexposedNot made visible
- first-lineTried before alternatives
- unmedicatedNot taking medicine
placebo-controlled
Tested against inactive substance
- comparatorTwo-input magnitude decider
- preclinicalBefore human trials
- enrollmentAct of registering officially
randomization · stratification · cohort · efficacy · tolerability · pharmacokinetics · dose-response · titration · sensitivity · responsiveness
untreated
Not given care
- baselineStandard for comparison
- unexposedNot made visible
- first-lineTried before alternatives