H1 receptor

Antihistamine binding site

H1 receptor refers to a type of histamine receptor found throughout the body, particularly in smooth muscle, blood vessels, and the brain.

When histamine binds to H1 receptors, it triggers allergic responses—itching, sneezing, swelling, and increased mucus production.

Antihistamines like diphenhydramine and loratadine work by blocking H1 receptors: The medication targets H1 receptors to reduce hay fever symptoms.

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itch · skin rash · hives · sneezing · watery eyes · itchy eyes · neurotransmitter · over the counter · nasal spray · sedation · wakefulness · brain · mast cell · inflammation · wheal · flare · hay fever · pollen

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Opposites
pharmacological action

H1 receptorantihistamine

Drug blocking allergic response

diphenhydramine · cetirizine · loratadine · chlorpheniramine · histamine

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