transmetalation

Organometallic partner trading

Transmetalation is a chemical reaction in which a metal atom or ion transfers from one molecule to another, exchanging places with a different metal.

The process is fundamental in organometallic chemistry and catalysis, enabling the synthesis of compounds that would be difficult to make otherwise: The palladium-catalyzed coupling proceeds via transmetalation from the boronic acid.

cross-coupling

Suzuki

Japanese motor vehicle corporation

turnover · selectivity

mechanism

oxidative addition

Metal cleaves and binds substrate

concerted · stepwise · thermodynamic · kinetic · activation energy

applications

natural product

Compound from living sources

drug discovery · scale-up · industrial process

Categories
Opposites
mechanistic steps in cross-coupling catalysis

transmetalationoxidative addition

Metal cleaves and binds substrate

Family

metal, transfer, transferable, trans, metallurgy, metalsmith

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Used worldwide · Timeless · Abstract · Rated G