loss of hope

• despairTotal absence of hope
• hopelessBeyond possibility of success
• desperationUtter loss of hope
• defeatVictory over another
• surrenderCease resistance, yield

giving up · darkness · emptiness · resignation · desolation · anguish · bleakness · futility · crushed · broken · sinking · drowning · abyss · void · nihilism · despondent · forlorn · dejected

• despairdespair, hopelessness, desolation, despondency, dejection
• sadnesssad, unhappy, grief, sorrowful, heartbroken