lassitudes

Lassitudes is the plural of lassitude, a state of physical or mental weariness, a lack of energy or enthusiasm.

The word is somewhat literary and suggests a deeper exhaustion than ordinary tiredness—a languor that settles over someone: The summer heat brought on lassitudes that made any effort feel pointless.

Multiple instances or varieties of this weariness are lassitudes: the lassitudes of age, the various lassitudes that afflict the chronically ill.