D2 receptor
Dopamine binding site
A D2 receptor is a type of dopamine receptor in the brain that regulates movement, motivation, and reward pathways.
D2 receptors are the primary target of antipsychotic medications, which block them to reduce symptoms of schizophrenia.
They also play a role in Parkinson's disease, addiction, and the brain's response to pleasurable stimuli.
- dopamineReward-linked neural messenger
- striatumSubcortical basal ganglia nucleus
- antipsychoticDrug treating psychosis
- schizophreniaPsychotic disorder with delusions
- basal gangliaSubcortical motor-control nuclei
haloperidol · agonist · antagonist · reward · addiction · addiction treatment · prolactin · cocaine · amphetamine · motivation · pleasure · binding · brain chemistry · neurotransmitter · synaptic · movement disorder · reward circuit · pituitary
- dopaminedopamine, dopamine release, DAT, tyrosine, MAO
- receptorsphotoreceptors, mechanoreceptors, mechanoreceptor, thermoreceptor, proprioceptor