Nerviest is the superlative of nervy, which has divergent meanings in British and American English.
In British usage, nerviest means most anxious or easily agitated: She was at her nerviest before the interview.
In American usage, it means most audacious or bold to the point of rudeness: That was the nerviest thing anyone's ever said to my face.
1. bold — audacious, Recklessly or disrespectfully fearless; gutsy (Informally courageous); ballsy (Daringly courageous, informal); brazen (Shamelessly bold); brash · cheeky · impudent · presumptuous · forward · pushy · shameless · insolent · impertinent · cocky
2. courageous — bravest, Having supreme valor; gutsiest (Most courageously bold)
3. anxious — jumpiest, Most easily startled; edgiest (Superlative of tense); shakiest (Least stable or secure)